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United trail 2-0 from the first leg at Old Trafford and they will have to produce a monumental performance to get the better of a PSG side that has suffered just one defeat from their last 22 home matches in all competitions.
Since losing to the defending French champions, the Red Devils have gone on a four-game unbeaten run and are still yet to taste defeat under interim boss Ole Gunnar Solskjaer on the domestic stage.
The visitors are walking wounded ahead of the contest, though, and they are without the injured Alexis Sanchez, Jesse Lingard, Ander Herrera, Nemanja Matic, Juan Mata, Anthony Martial and Phil Jones, while Paul Pogba is suspended.
United do boast an impressive record against French opponents, suffering just three defeats in 29 matches against 10 different clubs, but two of those losses have come against PSG (both 2-0 defeats).
Despite over two months of the season remaining, PSG already appear to have wrapped up the Ligue 1 title after opening up a 17-point lead at the top of the table with a game in hand.
Les Parisiens are on an eight-game winning streak in all competitions, also keeping six clean sheets during that run, and they have suffered just one defeat from their last 16 home Champions League games.
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