Usuthu have gone four league matches without win, having taken just two points from a possible 12 in the process.
They are currently lying 11th on the log with 28 points in 24 games.
The Urban Warriors on the other side, will be looking to beat AmaZulu and move out of the relegation zone.
Ajax are currently on 15th position, with 27 points in 24 games.
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