Mkhize and Lorch replace the injured Thapelo Morena and Vincent Pule.
Morena and Pule were released from the Bafana Bafana camp on Monday evening after being checked by the team medical team.
“They two received knocks during the weekend games and coach Baxter was hopeful that they would shake off the niggling injuries. But having checked them for most of Monday, Bafana Bafana team doctor Dr Thulani Ngwenya decided to release the two,” read a statement from Safa.
Bafana are set to play Seychelles in an Afcon qualifier at the FNB Stadium on Saturday. The match is set to kick off at 3pm.