Usuthu are winless in their last two league games having drawn 0-0 with Free State Stars at the Goble Park Stadium last week.
Sundowns extended their unbeaten run to five games in the league when they drew 1-1 with SuperSport United in the Tshwane Derby last weekend.
The Brazilians are sitting at the top of the league standings with 40 points from 22 games. They are four points above second-placed Orlando Pirates.
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