Platinum Stars and Bloemfontein Celtic will kick off the weekend action on Saturday afternoon at the Royal Bafokeng Stadium. Kick-off is at 3.30pm.
Later in the day, Bidvest Wits will welcome a confident Baroka FC team, who come to this clash having defeated defending champions Cape Town City at Bidvest Stadium at 8.15pm.
Also kicking off at 8.15pm on Saturday evening will be a match-up between Orlando Pirates and Polokwane City.
On Sunday, the Nelson Mandela Bay Stadium will play host to a clash between Chippa United and Kaizer Chiefs.
The TKO last-8 fixtures:
Saturday, November 4
Platinum Stars vs Bloemfontein Celtic – Royal Bafokeng Stadium (3.30pm)
Bidvest Wits vs Baroka FC – Bidvest Stadium (8.15pm)
Orlando Pirates vs Polokwane City – Orlando Stadium (8.15pm)
Sunday, November 5
Chippa United vs Kaizer Chiefs – Nelson Mandela Bay Stadium (3.30pm)
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