Sifiso Hlanti will make his national team debut at left back when he replaces the injured Thabo Matlaba. Rivaldo Coetzee started off the bench in the first leg through a forced change when Anele Ngcongca strained his calf muscle.
Thulani Serero will take the place of Mpho Makola in midfield, another player who misses out due to injury.
Mashaba’s men registered a 2-2 draw away in Limbe, Cameroon in the first leg on Saturday. They need a victory on Tuesday night to keep their chances of making it to Gabon 2017 alive.
South Africa starting XI v Cameroon in Durban:
Itumeleng Khune (capt), Thulani Hlatshwayo, Sifiso Hlanti, Rivaldo Coetzee, Erick Mathoho, Thulani Serero, Andile Jali, Hlompho Kekana, Mandla Masango, Tokelo Rantie, Thamsanqa Gabuza
Jackson Mabokgwane, Siyabonga Nhlapho, Asavela Mbekile, Kamohelo Mokotjo, Jabulani Shongwe, Ndumiso Mabena, Prince Nxumalo
Not considered for this match:
Darren Keet (injured), Anele Ngcongca (injured), Thabo Matlaba (injured), Mpho Makola (injured), William Twala, Cheslyn Jampies, Themba Zwane
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