Five players will make their international debut for Amajita.
The match will be played at Nkana Stadium in Kitwe at 3pm.
Amajita will be gunning for three points after Egypt went top of Group B with a 1-0 win over Mozambique on Wednesday.
South Africa starting XI: Khulekani Kubheka (GK); Sibusiso Mabiliso; Kamohelo Sambo; Thendo Mukumela (c); Keanu Cupido; Thabani Zuke; Nkosingiphile Ngcobo; George Matlou; Katlego Ntshabeleng; Happy Mashiane; Luvuyo Mkatshana
Subs: Sanele Tshabalala; Renaldo Leaner; Kiyaam Bull; Malebogo Modise; Bradley Cross; Patrick Maswanganyi; Sifundo Sibiya; Siphumelele Mbulu; Lyle Foster