The 27-year-old scored 11 goals this term back in France, after an ill-fated move from Bordeaux to northeast England in January 2016.
While his parent club were suffering a second straight relegation to drop into the English third tier, Khazri was helping Rennes finish fifth in Ligue 1 to qualify for European football for the first time since 2011/12.
Tunisia coach Nabil Maaloul sprung a surprise when he called up several European-based players for his 29-man preliminary World Cup squad who had not featured in qualifying.
Leicester defender Yohan Benalouane, Montpellier midfielder Ellyes Skhiri and Troyes youngster Saif-Eddine Khaoui were among those drafted in for Tunisia’s attempt to reach the knockout stage for the first time.
But Khazri has been a key figure for the Carthage Eagles over the last two years and was an integral part of the side which qualified for a first World Cup since 2006.
The winger scored twice in the final round of qualifying as Tunisia won Group A by one point ahead of the Democratic Republic of Congo, and netted his 12th international goal with the winner against Costa Rica in a friendly in March.
Maaloul’s team’s success has come from the foundation of a solid defence — they conceded just four goals in six qualifying group matches.
But they lack the star power to go toe-to-toe with World Cup Group G rivals Belgium and England, with none of their strikers based outside Africa or having scored 10 internationals goals.
Vice-captain Khazri has scored more times for his country than anyone else in the squad, and they may need him to produce a moment of magic if they’re to get the result they need against either England or the Belgians to progress from a group also including tournament debutants Panama.
Download our app and read this and other great stories on the move. Available for Android and iOS.