The protesters reportedly began barricading the road and burning tyres shortly after 10am, in the hope of voicing their frustrations surrounding the housing projects in Hlalani, which remain unfinished.
Local municipal law enforcement arrived soon after, along with representatives from the police.
While the public order policing service (POPS) was still en route to the protest, protesters began throwing rocks at law enforcement and police vehicles, cracking the windshield of a police van.
Soon after, however, POPS arrived on the scene and the crowd dispersed as the matter was brought under control.
The Knysna fire and rescue department was called in to douse the burning tyres and debris, and then cleanup crews were called in to remove the debris from the road in order to resume the flow of traffic.
Shortly after 12pm, the cleanups had been done traffic resumed in both directions.
This article first appeared on George Herald and was republished with permission.