Daily Covid-19 update: 1,294 cases, Pfizer vaccine ‘effective’ against SA strain

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By Hendri Pelser

South Africa added 1,294 new cases to the Covid-19 tally in the last 24 hours, Health Minister Dr Zweli Mkhize has announced.

In a statement on Thursday evening, he said that an additional 32,725 tests had been done and the recovery rate remained at 95%.

Almost 10 million South Africans have now been tested for the coronavirus. Just over a year ago, on the evening of 31 March 2020, South Africa had recorded an additional 46 new Covid-19 cases, bringing the national total to 1,353. The total number of tests on this day stood at 41,072.

Today, another 51 deaths were reported, bringing the official death toll to 52,897.

Just over 269,000 health care workers have been vaccinated.

Also today, the South African Health Products Regulatory Authority (SAHPRA) has approved the Johnson & Johnson (J&J) Covid-19 vaccine for mass distribution across the country.

This as as South Africa is expected to receive the first batch of an order of 30 million of the single-dose J&J vaccines manufactured locally by pharmaceutical giant Aspen in Gqeberha (formerly Port Elizabeth), Eastern Cape.

According to SAHPRA, individuals over the age of 18 are able to receive the J&J vaccine jab.

Pfizer/BioNTech say vaccine effective against SA variant

Pfizer and BioNTech said Thursday their Covid-19 vaccine was highly effective against the South African variant in the latest phase of ongoing clinical trials.

No cases of the disease were observed in South Africa during the phase-three trial study among participants who had received their second dose, the companies said in a statement.

Several coronavirus variants with the potential to be more transmissible have caused global concern over whether existing vaccines will still protect the world from a virus that is constantly mutating.

“In South Africa, where the B.1.351 lineage is prevalent and 800 participants were enrolled, nine cases of Covid-19 were observed, all in the placebo group,” the companies said.

The nine strains were sequenced and six of them were confirmed to be of B.1.351 lineage, they said.

“The high vaccine efficacy observed through up to six months following a second dose and against the variant prevalent in South Africa provides further confidence in our vaccine’s overall effectiveness,” said Albert Bourla, chief executive of Pfizer.

Overall, the vaccine was 91.3 percent effective against Covid-19 in the analysis of 46,307 trial participants across several countries.

From the 927 confirmed symptomatic cases of Covid-19 in the trial, 850 cases were in the placebo group and 77 cases were in the vaccinated group.

The vaccine was 100 percent effective in preventing severe disease as defined by the US Centers for Disease Control and Prevention, and 95.3 percent effective in preventing severe disease as defined by the US Food and Drug Administration.

Pfizer and BioNTech had said in January that “small differences” detected in tests comparing the original virus and the recent versions “are unlikely to lead to a significant reduction in the effectiveness of the vaccine”.

The companies said Thursday the new data “support previous results from immunogenicity studies demonstrating that (the vaccine) induced a robust neutralising antibody response to the B1.351 (South African) variant, and although lower than to the wild-type strain, it does not appear to affect the high observed efficacy against this variant”.

Global deaths from Covid-19 have topped 2.8 million since the pandemic began a year ago, with vaccines seen as the only real chance of returning to some form of normality.

Coronavirus: Latest global developments

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2.8 million dead

At least 2,816,908 people have died of Covid-19 around the world since the outbreak emerged in China in December 2019, according to an AFP tally from official sources.

The US is the worst-affected country with 552,073 deaths followed by Brazil with 321,515 fatalities, Mexico with 203,210, India with 162,927 and Britain with 126,713 deaths.

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By Hendri Pelser
Read more on these topics: Coronavirus (Covid-19)Infection Updates