Cannabis first cultivated 12,000 years ago: study

Cannabis was first domesticated around 12,000 years ago in China, researchers found, after analysing the genomes of plants from across the world.

The study, published in the journal Science Advances on Friday, said the genomic history of cannabis domestication had been understudied compared to other crop species, largely due to legal restrictions.

The researchers compiled 110 whole genomes covering the full spectrum of wild-growing feral plants, landraces, historical cultivars, and modern hybrids of plants used for hemp and drug purposes.

The study said it identified “the time and origin of domestication, post-domestication divergence patterns and present-day genetic diversity”.

“We show that cannabis sativa was first domesticated in early Neolithic times in East Asia and that all current hemp and drug cultivars diverged from an ancestral gene pool currently represented by feral plants and landraces in China,” it said.

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‘New insights’ –

The study was led by Luca Fumagalli of the University of Lausanne and involved scientists from Britain, China, India, Pakistan, Qatar and Switzerland.

“Our genomic dating suggests that early domesticated ancestors of hemp and drug types diverged from Basal cannabis”, around 12,000 years ago, “indicating that the species had already been domesticated by early Neolithic times”, it said.

“Contrary to a widely accepted view, which associates cannabis with a Central Asian centre of crop domestication, our results are consistent with a single domestication origin of cannabis Sativa in East Asia, in line with early archaeological evidence.”

It said that some of the wild plants currently found in China represent the closest descendants of the ancestral gene pool from which hemp and marijuana varieties have since derived.

“East Asia has been shown to be an important ancient hot spot of domestication for several crop species… our results thus add another line of evidence,” the study said.

The researchers said their study offered an “unprecedented” base of genomic resources for ongoing molecular breeding and functional research, both in medicine and in agriculture.

The study, they said, also “provides new insights into the domestication and global spread of a plant with divergent structural and biochemical products at a time in which there is a resurgence of interest in its use, reflecting changing social attitudes and corresponding challenges to its legal status in many countries.”