Simbine clocked 10.09 seconds to win the men’s short sprint, well clear of second-placed Brent Stevens who clocked 10.49.
The 21-year-old Tuks athlete chopped 0.04 off his season’s best set at the Gauteng North provincial championships last week, racking up the seventh fastest time in SA history.
He was 0.07 outside his career record set last year and 0.11 off Simon Magakwe’s national best.
“It’s a good victory and I’m really excited about it,” Simbine said.
“The standard here is high which helps me gauge myself in the build-up to the international season.”
Simbine and Justine Palframan of Maties received the Victor and Victrix Ludorum awards.
Palframan won the women’s 200m (23.73) and 400m (54.20) races less than an hour apart.
Defending champions Tuks took the overall series lead with 127 points, followed by hosts Pukke (117) and Kovsies (89).
World champions Viteslav Vesely of the Czech Republic (javelin throw) and Bohdan Bondarenko of the Ukraine (high jump), both currently training in Potchefstroom, attended the event though neither took part as the series is open only to SA-based students.
The second of two legs in the Varsity Athletics campaign will be held in Stellenbosch on April 20.