The backline consist of some the most exciting talent in the country with fullback Jesse Kriel and centre William Small-Smith earning a starting berth ahead of Jurgen Visser and JJ Engelbrecht, respectively.
Flyhalf Tony Jantjies comes in for the injured Jacques-Louis Potgieter and will partner scrumhalf Rudy Paige, who replaces Piet van Zyl.
Hooker Bongi Mbonambi will earn a start in place of Callie Visagie, who drops out of the match-day 22.
In the front row Marcel van der Merwe moves from loosehead to tighthead with Dean Greyling returning after a week’s suspension.
Blue Bulls team: Jesse Kriel, Akona Ndungane, William Small-Smith, Burger Odendaal, Sampie Mastriet, Tony Jantjies, Rudi Paige, Jono Ross, Jacques du Plessis, Deon Stegmann (captain), Grant Hattingh, Paul Willemse, Marcel van der Merwe, Bongi Mbonambi, Dean Greyling. Replacements: Bandise Maku, Werner Kruger, Nicolaas Janse van Rensburg, Wiaan Liebenberg, Piet van Zyl, Joshua Stander, Ulrich Beyers.