The coastal side missed out on automatic qualification for the semi-finals after ending in third position on the log.
They have to beat the New Zealanders at Kings Park, before heading overseas to try and upstage the Crusaders in the semi-finals in Christchurch.
Only once in the competition’s history has a team travelled out of their own country to win the title.
“You guys write that 12 out of 18 games have been won by teams that have hosted the final, well Brazil lost 7-1 at home to Germany,” White said ahead of the game.
“If I told people that before the World Cup, they would have laughed at me.
“That is what sport does, and it’s going to happen that a team which doesn’t finish in the top two is going to win this competition. It has to happen.”
The Sharks, however, must first negotiate the first part of their quest, which is to overcome the Otago-based visitors, who are the only overseas team to have won in Durban this year.
Back in April, they enjoyed a surprise 34-18 victory and White was quick to take the blame for that loss, which was their final game before one of their most successful overseas tours in history.
“I don’t think we took them lightly, you can’t afford that against anyone in this competition,” White said.
“I took the blame for that and it was mainly because I erred in selection. There were a lot of things I toyed with before we left on tour.
“I’m not for one minute suggesting we took anything for granted against them. It was my own fault.”
White, whose side were 34-10 winners over the Stormers last week, made one change to his XV bringing back Cobus Reinach for Charl McLeod at scrumhalf.
He also included flyhalf Patrick Lambie in his squad for the first time since March after a long-term injury.
The Sharks coach said his charges could not afford to look beyond the Highlanders, who will feature in the playoffs for the first time since 2002.