Stonehouse included inside centre Stefan Watermeyer, who was a regular feature during the Lions’ Super Rugby campaign.
Watermeyer, the only Super Rugby player considered for the starting XV with scrumhalf Faf de Klerk and fullback Coenie van Wyk out with injury, will form a midfield combination with JW Jonker.
Prop Corne Fourie has been named on the bench with Vincent Koch receiving the nod ahead of him.
Scrumhalf Reynier van Rooyen will form a halfback combination with Justin van Staden.
JW Bell will be in the last line of defence, forming a back trio with Springbok Sevens players Rosco Speckman and Ruwellyn Isbell.
Pumas team: JW Bell, Ruwellyn Isbell, JW Jonker, Stefan Watermeyer, Rosco Speckman, Justin van Staden, Reynier van Rooyen, Renaldo Bothma, Jaco Bouwer, Corne Steenkamp (captain), Marius Coetzer, Frikkie Spies, DeJay Terblanche, Francois du Toit, Vincent Koch. Replacements: Frankie Herne, Corne Fourie, Giant Mtyanda, Uzair Cassiem, Snake Nyoka, JC Roos, Jerome Pretorius.