Serious Versus Deadly Snakebites

Roughly 11% of the 173 species of snakes in southern Africa can be considered deadly and these include mambas, cobras, the Rinkhals, Puff Adder, Gaboon Adder, Boomslang and the Twig Snake.

The Mozambique Spitting Cobra accounts for the vast majority of serious bites, followed by the Puff Adder, and then the Stiletto Snake and Rhombic Night Adder. Most of the deaths resulting from snakebite in southern Africa are a result of Cape Cobra and Black Mamba bites.

The vast majority of snakebite victims who are hospitalised soon after a bite, will survive. No more than 15% of snakebite victims will require antivenom.

How to Avoid Getting Bitten

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Snakebite Symptoms

Snakebite symptoms vary dramatically from bite to bite. Many snakebites take place so quickly that victims are not always certain that they have actually been bitten. A bite mark is seldom the characteristic two-fang puncture mark – often a bite will be from a single fang and may just be a scratch with a little bleeding. In the event of a snakebite, the victim may have some of the following symptoms

In the Event of A Snakebite DO NOT…

First Aid Measures for Snakebite

IMPORTANT!!! Do not waste valuable time applying a pressure bandage – immediately transport the patient to the nearest hospital with a trauma unit and, if possible, apply the pressure bandage whilst travelling.

Pressure Bandages

Pressure immobilisation may be beneficial and inhibit the spread of venom while the victim is transported to hospital. It should not be used in spitting cobra or adder bites where excessive swelling is anticipated, but rather for bites from the Cape Cobra and Black Mamba. The idea is not to slow down blood flow, but rather to put pressure on the lymphatic system and, in doing so, reduce the rate at which venom is absorbed. The application of a pressure bandage is rather complex and requires training to get the pressure right. Ideally make use of a Smart bandage.

Application of a Pressure Bandage

New Smart Bandages, with printed rectangles that have to be stretched until the rectangles form perfect squares, have made the proper application of pressure bandages far easier.

Artificial Respiration

In serious snakebite cases involving snakes with predominantly neurotoxic venom, like the Black Mamba or Cape Cobra, the victim may experience difficulty with breathing. In severe cases, especially where small children are involved, this could happen within less than half an hour. In such instances, begin mouth-to- mouth resuscitation. Assisted breathing while transporting the victim to hospital can be life-saving. If you are far away from the nearest hospital, or on a remote farm or travel into the bush often, seriously consider acquiring a bag valve mask (BVM) and undergoing the required training to learn how to use it. If properly used, it can keep a victim alive for several hours.

Using a Bag Valve Mask

Using a Bag Valve Mask requires training. It can be used if the patient stops breathing or has severe difficulty in breathing. The idea is to lay the patient on his/her back, tilt the head backwards to open up the airway and ensure that there is no blockage or excessive liquid that could block the airway.

Advantages of using a bag valve mask

Disadvantages of using a bag valve mask

Spitting Snakes

The common spitting snakes in South Africa are the Mozambique Spitting Cobra (M’Fezi) and the Rinkhals. In addition to biting, both of these snakes spray their venom up to a distance of three metres and do so in self-defence to temporarily blind their attacker and allow the snake to escape.

What to do

Pets, Farm Animals and Snakebite

Many dogs are bitten by snakes, usually while trying to kill a snake. Cats are very quick and smart enough to attack juvenile snakes only and are seldom bitten. Farm animals, including sheep, goats, horses and cows may suffer from snake bites, usually on the face or neck, and this may result in severe swelling and tissue damage.

Popular myths that are meaningless in saving your pet or farm animal after a snakebite

The bite from a neurotoxic snake (largely mambas and some cobras) may cause respiratory paralysis and threaten the animal’s life. Such animals may die without antivenom and/or assisted ventilation. Should the animal stop breathing on the way to a veterinarian, you can try mouth-to-nose resuscitation.

These animals will probably need antivenom and will likely have to be placed on a ventilator to help them breathe while the antivenom takes effect. Bites from snakes with predominantly cytotoxic venom – such as adders and spitting cobras – result in pain, swelling and blistering and this may lead to tissue damage. Small animals may suffer severe blood loss in addition to tissue damage.

In cases where dogs are bitten in the face and throat region the swelling may also inhibit breathing and this is particularly problematic in small dogs. Animals that are severely envenomed may die as a result of hypovolemic shock and/or tissue necrosis and cell death. In cases of severe envenomation, antivenom is the only solution and anything from two to six (or more) vials of polyvalent antivenom (polyvalent antivenom neutralises the venom of cobras, mambas, the Rinkhals, Puff Adder and Gaboon Adder) may be required.

Such treatments cost anything from R4, 000 to over R20, 000.

For venom in the eyes, the treatment is like that for humans. Gently rinse the eyes with water for 15 – 20 minutes and get the dog to a veterinarian who will apply local anaesthetic and antibiotic eye drops. If the correct procedures are followed, most dogs regain full sight within a few days.

There is very little an owner can do to save an animal’s life that has been bitten by a venomous snake, other than getting it to a vet. Home remedies and first aid treatment has very little effect on the final outcome of such a bite.

Know Your Venom

Snake venom is complex in composition and varies dramatically from species to species. There may even be variation in the potency of venom within the same species.

Snake venom is generally divided into three categories based on the toxins it contains: 

Neurotoxins (the mambas and several of the cobras, especially the Cape Cobra), Cytotoxins (the Puff Adder, Gaboon Adder and Mozambique Spitting Cobra), and Haemotoxins (the Boomslang and the Twig Snake). However, these are broad categorisations and do not cover all the complexities or combinations of venom – the venom of the Forest Cobra, for example, contains a mixture of both neurotoxins and cytotoxins. So when we say that a snake has neurotoxic or cytotoxic venom, it is a generalisation and refers to the dominant clinical effects.

Neurotoxic venom affects the nervous system

Symptoms may include drowsiness, vomiting, increased sweating, blurred vision, drooping eyelids, slurred speech and difficulty in swallowing, speaking, breathing and weakness of other muscle groups. The respiratory muscles are gradually paralysed which leads to respiratory failure. Snakes with predominantly neurotoxic venom include the Black Mamba, Green Mamba, and some non-spitting cobras.

Cytotoxic venom affects the tissue and muscle cells

Symptoms may include immediate burning pain at the site of the bite followed by local swelling that could continue for several days. In severe cases the entire limb may swell. Local tissue necrosis is quite common and may result in the loss of a limb. Snakes with predominantly cytotoxic venom include the Puff Adder, Rhombic Night Adder, Mozambique Spitting Cobra and Stiletto Snake.

Hemotoxic venom affects the clotting mechanism of the blood

There is usually little or no swelling and very little pain initially. The bite is followed by oozing of blood from the bite site after a few hours, headache, mental confusion, nausea, vomiting and increased sweating.

After several hours there may be bleeding from small cuts, the mucous membranes of the mouth and nose, purple patches under the skin, and eventually severe internal bleeding which results in vomiting of blood and haemorrhage from the bowels. Kidney failure and brain haemorrhage may occur after a few days.

Antivenom

The development of antivenom

Antivenom was first used in 1886 and, in 1901, the first South African antivenom was produced in Pietermaritzburg in small quantities. A complete first aid kit contained a lancet, ligature, syringe and two bottles of serum. In 1928, the South African Institute for Medical Research (SAIMR) began to produce antivenom.

They experimented with a variety of domestic animals for serum production, but settled on the horse, due to the large volume of blood that could be tapped during a session. Initially, antivenom production was limited to the venom of the Cape Cobra and Puff Adder, but in 1938, Gaboon Adder venom was introduced.

The venom of the three southern African mambas were added to the polyvalent antivenom in 1971. During the 1970s the venoms of various other cobras were also added. A monovalent antivenom was developed for the venom of the Boomslang in 1940.

Antivenom today

South African Vaccine Producers in Johannesburg manufacture a monovalent antivenom that is effective against the venom of the Boomslang, a polyvalent antivenom that provides protection against the venom of the Puff Adder, Gaboon Adder, Black and Green Mambas, the Rinkhals and all of the dangerous cobras in southern Africa, as well as a monovalent antivenom for the Saw-scaled Viper that does not occur within our range. Snakebite kits contain two 10 ml vials of antivenom and can be purchased directly from the SAVP.

The kit must be refrigerated, not frozen, at 2-10 ºC. Any exposure to high temperatures will alter its effectiveness. The kit has a three-year shelf life; each vial has an expiry date beyond which it should not be used. Antivenom is NOT a first-aid measure and, if required, should be injected by a doctor in a hospital environment.

The dosage depends on the amount of venom injected, rather than the weight of the victim; a child will therefore receive the same amount of antivenom as an adult. Most snakebite victims that are treated with antivenom receive 8 – 12 vials. Up to 40% of patients treated with antivenom may experience an allergic reaction.

In some cases patients go into anaphylaxis, a life-threatening condition during which the blood pressure drops and the heart may stop beating. Doctors treat such patients with adrenaline.

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