Police received information about a wanted man in T Section, Umlazi, on Friday and went to the location, said Colonel Jay Naicker.
When police arrived, they found the man and identified themselves to him, said Naicker.
Police claim the man produced a firearm and pointed it at police.
Naicker said the man was shot and killed by police.
A case of murder was opened, and the Independent Police Investigative Directorate was investigating.
Claims by the Inkatha Freedom Party that it was their member who was killed could not be confirmed by police.