Barileng Pholoholo, 40, was granted bail at R500, Colonel Sabata Mokgwabone said.
She would appear in court again on April 30.
Pholoholo was arrested on Monday.
“Police were called to a certain house in Rooigrond [Mahikeng] where a 53-year-old man was found dead with multiple stab wounds on the body.
“The victim was certified dead on the scene and the suspect, who was found in possession of a blood-covered knife in her hand, was arrested,” Mokgwabone said.