Two people sustained moderate injuries when a bus collided with a vehicle on the N4 in Matsulu.
The exact detail to the cause of the accident will remain a subject for police investigation and comment.
Read: Five killed in Acornhoek accident
Netcare911 paramedics worked alongside other services on scene.
Two people were stabilised on scene and thereafter transported to a nearby hospital for further medical care.
Also read: Ten Mozambicans killed in road accident
The accident happened on Tuesday afternoon.
