The men from Pretoria held a 20-0 lead at the break and kept increasing that margin in a second half that saw 78 points being scored.
In the second match on Sunday, DHL Western Province scored a crucial try at the final buzzer as they beat Toyota Free State by 47-28, keeping alive their chances to make it to the final on October 30.
The late try secured the Capetonians a bonus point as they moved from the bottom of the log to third place and back into contention with one round of pool matches remaining.
Next Sunday, the Cell C Sharks and Toyota Free State, both with four log points, will kick off at 10.30am, and the match between DHL Western Province (five points) and the Xerox Lions (nine points), which is likely to deliver the other finalist, starts at 1.45pm.
The Vodacom Blue Bulls are the defending champions and have a bye next Sunday, but their big win over the Cell C Sharks guaranteed them top spot on the log (15 log points), so all eyes will be on the remaining four teams next Sunday, all of whom still have a mathematical change to qualify for the October 30 showpiece.
