The World Health Organisation announced that the hydroxychloroquine (HCQ) arm of the Solidarity Trial to find an effective Covid-19 treatment has been stopped.
The organisation stated that the trial’s executive group and principal investigators made the decision based on evidence from the Solidarity Trial, the United Kingdom’s recovery trial and a Cochrane review of other evidence on hydroxychloroquine.
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“Data from Solidarity, including the French Discovery trial data, and the recently announced results from the UK’s recovery trial, both showed that hydroxychloroquine does not result in the reduction of mortality of hospitalised Covid-19 patients when compared with standard of care,” the organisation stated.
Investigators will not randomise further patients to hydroxychloroquine in the Solidarity Trial.
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Patients who have already started hydroxychloroquine, but who have not yet finished their course in the trial may complete their course or stop at the discretion of the supervising physician.
“This decision applies only to the conduct of the Solidarity Trial and does not apply to the use or evaluation of hydroxychloroquine in pre- or post-exposure prophylaxis in patients exposed to Covid-19.”
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